Long-term treatment of double depression: A preliminary study with serotonergic antidepressants

@article{Hellerstein1994LongtermTO,
  title={Long-term treatment of double depression: A preliminary study with serotonergic antidepressants},
  author={D. Hellerstein and P. Yanowitch and J. Rosenthal and Camille Hemlock and A. Winston},
  journal={Progress in Neuro-Psychopharmacology and Biological Psychiatry},
  year={1994},
  volume={18},
  pages={139-147}
}
1. There is increasing evidence that many patients with major depression also have coexisting dysthymia, and that antidepressant treatment may alleviate both conditions. 2. Open-label study of fluoxetine and trazodone for 18 patients meeting DSM-III-R criteria for concurrent dysthymia and major depression. 3. Fourteen patients completed three-month medication trials, and seven (50%) of completers) responded to treatment. At five months, eight (57.1%) were in remission. Fluoxetine was… Expand
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