Long-term treatment of chronic depression: 15-year experience with doxepin HCl.

  • Frank J Ayd
  • Published 1984 in The Journal of clinical psychiatry


The definition, recognition, and management of chronic depression are briefly reviewed. An ongoing prospective study of the long term (5-15 years) use of doxepin indicates that this tricyclic antidepressant is feasible, efficacious, and safe in the treatment of this population. Advantages of doxepin therapy include its lack of adverse interactions with… (More)


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