Long-term therapy with deferiprone.

  title={Long-term therapy with deferiprone.},
  author={Nancy F. Olivieri},
  journal={Acta haematologica},
  volume={95 1},
Data from several trials have provided direct and supportive evidence for the efficacy of deferiprone in the treatment of iron overload in thalassemia major. Deferiprone has been shown to induce sustained decreases in body iron to concentrations associated with survival free from the complications of iron overload in deferoxamine (DFO)-treated patients. Despite this evidence of efficacy, the risk of agranulocytosis mandates a careful evaluation in patients willing and able to use DFO. The… CONTINUE READING

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Role of Iron Chelation Therapy in Thalassemia Major.

Turkish journal of haematology : official journal of Turkish Society of Haematology • 2002
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