Long-term therapeutic effect of novel calcium phosphate-based compounds injected in ovariectomized rats.

@article{Tokudome2009LongtermTE,
  title={Long-term therapeutic effect of novel calcium phosphate-based compounds injected in ovariectomized rats.},
  author={Yoshihiro Tokudome and Makoto Otsuka and Atsuo Ito and Racquel Z Legeros},
  journal={Journal of biomedical materials research. Part B, Applied biomaterials},
  year={2009},
  volume={90 1},
  pages={229-37}
}
The specific aim of this study was to evaluate the efficacy of well-characterized Mg/Zn/F-CaP preparations (administered by injection) in preventing bone mineral deficiency in ovariectomized (OVX) rats. Donryu rats (4 weeks old, average weight 70 g) were divided into six experimental groups: GN (normal), GC (control, OVX), and OVX rats injected with… CONTINUE READING