Long-term survival of dopaminergic neurones in free-floating roller tube cultures of human fetal ventral mesencephalon.

@article{Spenger1994LongtermSO,
  title={Long-term survival of dopaminergic neurones in free-floating roller tube cultures of human fetal ventral mesencephalon.},
  author={Christian Spenger and Lorenz Studer and Ljudmila Evtouchenko and Marcel Egli and Jean-Marc Burgunder and Regula Markwalder and Rolf W. Seiler},
  journal={Journal of neuroscience methods},
  year={1994},
  volume={54 1},
  pages={63-73}
}
Transplantation of human fetal ventral mesencephalon (VM) to Parkinsonian patients has shown beneficial effects in several clinical trials. However, further improvements in the transplantation technique are needed. Delayed surgery, i.e., the in vitro maintenance of the tissue prior to transplantation would present several advantages. The roller tube technique as initially described by Gähwiler (1981) was modified in several aspects for the long-term maintenance of dopaminergic neurones of human… CONTINUE READING
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