Corpus ID: 87546238

Long-term stromal cultures produce dendritic-like cells

@inproceedings{Ia1997LongtermSC,
  title={Long-term stromal cultures produce dendritic-like cells},
  author={Kozlova Ia},
  year={1997}
}
  • Kozlova Ia
  • Published 1997
  • Biology
  • Summary. A stromal cell-dependent long-term culture (LTC) system has been developed from spleen which continuously generates non-adherent cells with dendritic cell (DC) characteristics. Bioassays using factor-dependent cell lines have revealed that both spleen and thymic stromal cultures secrete interleukin (IL)-3 and IL-6-like growth factors. Conditioned medium from LTC also contains factors which appear to be unrelated to IL-3 and induces growth of stromal cells from bone marrow. Non-adherent… CONTINUE READING

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