Long-term stability of effects of subthalamic stimulation in Parkinson's disease: Indian Experience.

@article{Kishore2010LongtermSO,
  title={Long-term stability of effects of subthalamic stimulation in Parkinson's disease: Indian Experience.},
  author={Asha Kishore and Ravimohan Rao and Syam Krishnan and Dilip Panikar and Gangadhara Sarma and Mathuranath Pavagada Sivasanakaran and Sankara P. Sarma},
  journal={Movement disorders : official journal of the Movement Disorder Society},
  year={2010},
  volume={25 14},
  pages={2438-44}
}
Reports of long-term effects of subthalamic (STN) stimulation for Parkinson's disease (PD) are few, mostly open-label evaluations and from Western centers. We used single-blind and open-label motor, cognitive and quality of life (QOL) evaluations to study the effects of bilateral STN stimulation in 45 patients over 5 years. Our patients showed a stable and substantial reduction in the cardinal signs of PD, motor fluctuations, and dyskinesias but less so for axial signs. The reduction in… CONTINUE READING

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