Long-term stability and circadian variation in circulating levels of surfactant protein D.

@article{Hoegh2010LongtermSA,
  title={Long-term stability and circadian variation in circulating levels of surfactant protein D.},
  author={S V Hoegh and Grith Lykke Sorensen and Ida Tornoe and Tine Lottenburger and Henriette Ytting and Hans J\orgen Nielsen and Peter Junker and Uffe Holmskov},
  journal={Immunobiology},
  year={2010},
  volume={215 4},
  pages={314-20}
}
Surfactant protein D (SP-D) is an oligomeric calcium-dependent lectin with important roles in innate host defence against infectious microorganisms. Several studies have shown that patients with inflammatory lung disease have elevated levels of circulating SP-D, and serum SP-D has been suggested to be used as a biomarker for disease e.g. in COPD. We aimed to investigate the variation of circulating SP-D in healthy individuals in and between days for 6 months. In addition, we studied the SP-D… CONTINUE READING