Long-term shifts in patterns of antibiotic resistance in enteric bacteria.

@article{Houndt2000LongtermSI,
  title={Long-term shifts in patterns of antibiotic resistance in enteric bacteria.},
  author={T Houndt and Howard Ochman},
  journal={Applied and environmental microbiology},
  year={2000},
  volume={66 12},
  pages={5406-9}
}
Several mechanisms are responsible for the ability of microorganisms to tolerate antibiotics, and the incidence of resistance to these compounds within bacterial species has increased since the commercial use of antibiotics became widespread. To establish the extent of and changes in the diversity of antibiotic resistance patterns in natural populations, we… CONTINUE READING