Long-term running alleviates some behavioral and molecular abnormalities in Down syndrome mouse model Ts65Dn.

@article{Kida2013LongtermRA,
  title={Long-term running alleviates some behavioral and molecular abnormalities in Down syndrome mouse model Ts65Dn.},
  author={Elizabeth Kida and Ausma Rabe and Marius Walus and Giorgio Albertini and Adam A. Golabek},
  journal={Experimental neurology},
  year={2013},
  volume={240},
  pages={178-89}
}
Running may affect the mood, behavior and neurochemistry of running animals. In the present study, we investigated whether voluntary daily running, sustained over several months, might improve cognition and motor function and modify the brain levels of selected proteins (SOD1, DYRK1A, MAP2, APP and synaptophysin) in Ts65Dn mice, a mouse model for Down syndrome (DS). Ts65Dn and age-matched wild-type mice, all females, had free access to a running wheel either from the time of weaning (post… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS
11 Citations
89 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 89 references

Brain plasticity and environmental enrichment in Ts65Dn mice, an animal model for Down syndrome

  • A. Golabek, K. Jarzabek, +4 authors E. Kida
  • 2011
Highly Influential
4 Excerpts

Similar Papers

Loading similar papers…