Long-term results of the R-CHOP study in the treatment of elderly patients with diffuse large B-cell lymphoma: a study by the Groupe d'Etude des Lymphomes de l'Adulte.

@article{Feugier2005LongtermRO,
  title={Long-term results of the R-CHOP study in the treatment of elderly patients with diffuse large B-cell lymphoma: a study by the Groupe d'Etude des Lymphomes de l'Adulte.},
  author={Pierre Feugier and Achiel van Hoof and Catherine Sebban and Philippe Solal-C{\'e}ligny and R{\'e}da Bouabdallah and Christophe Ferm{\'e} and Bernard Christian and Eric Lepage and Herv{\'e} Tilly and Franck Morschhauser and Philippe Gaulard and Gilles Salles and Andr{\'e} Bosly and Christian Gisselbrecht and Fidel Aroche Reyes and Bernard Coiffier},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2005},
  volume={23 18},
  pages={
          4117-26
        }
}
PURPOSE To analyze the long-term outcome of patients included in the Lymphome Non Hodgkinien study 98-5 (LNH98-5) comparing cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) to rituximab plus CHOP (R-CHOP) in elderly patients with diffuse large B-cell lymphoma. PATIENTS AND METHODS LNH98-5 was a randomized study that included 399 previously untreated patients, age 60 to 80 years, with diffuse large B-cell lymphoma. Patients received eight cycles of classical CHOP… CONTINUE READING

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