Long-term results of a randomized trial of surgery with or without preoperative chemotherapy in esophageal cancer.

Abstract

PURPOSE OEO2 is a randomized, controlled trial of preoperative chemotherapy in patients undergoing radical surgery for esophageal cancer. Random assignment was to surgery alone (S) or to two cycles of combination cisplatin and fluorouracil before surgery (CS). Initial results reported in 2002 demonstrated an advantage for both disease-free and overall… (More)
DOI: 10.1200/JCO.2009.22.2083

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