Long-term results of a randomized controlled trial in childhood IgA nephropathy.

  title={Long-term results of a randomized controlled trial in childhood IgA nephropathy.},
  author={Koichi Kamei and Koichi Nakanishi and Shuichi Ito and Mari Saito and Mayumi Sako and Kenji Ishikura and Hiroshi Hataya and Masataka Honda and Kazumoto Iijima and N. Yoshikawa},
  journal={Clinical journal of the American Society of Nephrology : CJASN},
  volume={6 6},
BACKGROUND AND OBJECTIVES Children with IgA nephropathy showing diffuse (>80%) mesangial proliferation are at high risk for end-stage renal failure (ESRF). A previous controlled trial showed that combination therapy consisting of prednisolone, azathioprine, heparin-warfarin, and dipyridamole early in the course of disease reduces immunologic renal injury and prevents the progression of sclerosed glomeruli. The objective of this study was to evaluate the long-term effectiveness of combination… CONTINUE READING


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Combination therapy with mizoribine for severe childhood IgA nephropathy : A pilot study

  • K Nakanishi, N Yoshikawa
  • 2008

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