Long-term results in children with AML: NOPHO-AML Study Group – report of three consecutive trials

@article{Lie2005LongtermRI,
  title={Long-term results in children with AML: NOPHO-AML Study Group – report of three consecutive trials},
  author={Sverre Olaf Lie and Jonas Abrahamsson and Niels Clausen and Erik Forestier and Henrik Hasle and Liisa Hovi and G Jonmundsson and Lotta Mellander and Martti A. Siimes and M. Yssing and Bernward Zeller and G{\"o}ran Gustafsson},
  journal={Leukemia},
  year={2005},
  volume={19},
  pages={2090-2100}
}
In all, 447 children with acute myeloid leukaemia (AML) have been treated on three consecutive NOPHO studies from July 1984 to December 2001. NOPHO-AML 84 was of moderate intensity with an induction of three courses of cytarabine, 6-thioguanine and doxorubicin followed by four consolidation courses with high-dose cytarabine. The 5-year event-free survival (EFS), disease free survival (DFS) and overall survival (OS) were 29, 37 and 38%. NOPHO-AML 88 was of high intensity with the addition of… CONTINUE READING
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