Long-term restoration of damaged corneal surfaces with autologous cultivated corneal epithelium

@article{Pellegrini1997LongtermRO,
  title={Long-term restoration of damaged corneal surfaces with autologous cultivated corneal epithelium},
  author={Graziella Pellegrini and Carlo Enrico Traverso and Adriano T. Franzi and Mario Zingirian and Michele de Luca},
  journal={The Lancet},
  year={1997},
  volume={349},
  pages={990-993}
}
BACKGROUND Complete loss of the corneal-limbal epithelium leads to re-epithelialisation by bulbar conjunctival cells. Since conjunctival and corneal-limbal epithelial cells represent two different cell lines, this conjunctival healing of the cornea is followed by stromal scarring, decreased visual acuity, and severe discomfort. Unilateral corneal-limbal epithelial defects can be resolved by the transplantation of limbal grafts taken from the uninjured eye. However, this procedure requires a… CONTINUE READING

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