Long-term regulation of AMP-activated protein kinase and acetyl-CoA carboxylase in skeletal muscle.

Abstract

Evidence is accumulating for roles of AMP-activated protein kinase (AMPK) in controlling glucose uptake, fatty acid oxidation and gene expression in skeletal muscle. Relatively little is known, however, about the control of expression of the AMPK subunit isoforms. Marked differences are noted in subunit expression as a function of muscle fibre type… (More)

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