Long-term prognosis of early-onset breast cancer in a population-based cohort with a known BRCA1/2 mutation status

@inproceedings{Nilsson2014LongtermPO,
  title={Long-term prognosis of early-onset breast cancer in a population-based cohort with a known BRCA1/2 mutation status},
  author={Martin P Nilsson and Linda Hartman and Ingrid Idvall and Ulf Kristoffersson and Oskar Thor Johannsson and Niklas Loman},
  booktitle={Breast Cancer Research and Treatment},
  year={2014}
}
All women in the South Sweden Health Care Region with breast cancer diagnosed aged less than 41 during the period between 1990 and 1995 were contacted in 1996 and offered germline mutation analysis of the BRCA1 and BRCA2 genes. Mutation carriers (n = 20) were compared with noncarriers (n = 201) for overall survival (OS) and risk of contralateral breast cancer (CBC). Mutation carriers were younger at diagnosis and more likely to have ER-negative, PgR-negative and grade III tumors. Median follow… CONTINUE READING

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