Long-term potentiation of the perforant path-granule cell synapse in the rat hippocampus

@article{Douglas1975LongtermPO,
  title={Long-term potentiation of the perforant path-granule cell synapse in the rat hippocampus},
  author={R. Douglas and G. V. Goddard},
  journal={Brain Research},
  year={1975},
  volume={86},
  pages={205-215}
}
  • R. Douglas, G. V. Goddard
  • Published 1975
  • Biology, Medicine
  • Brain Research
  • When the entorhinal cortex is electrically stimulated, a monosynaptic evoked potential is produced in the ipsilateral hippocampus. Twenty-four hours after a 120-pulse stimulation train, the response to a single test pulse was found to be increased. Stimulation trains presented at a rate of 1/day had a cumulative effect on both the population EPSP and spike components of the evoked potential, and the potentiation so produced lasted at least 12 days. In a few cases, retested 2 months after the… CONTINUE READING
    Long-term potentiation in the hippocampus
    • 441

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