Long-term potentiation of the human blink reflex.

  title={Long-term potentiation of the human blink reflex.},
  author={JQ. Mao and Craig Evinger},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  volume={21 12},
The trigeminal reflex blink is an ideal system to investigate whether stimulus paradigms that produce long-term potentiation (LTP) in vitro modify motor learning in humans. Presentation of 12 trains of low-intensity, high-frequency stimuli (HFS) to the supraorbital branch of the trigeminal nerve (SO) modified subsequent reflex blinks of human subjects. When HFS occurred concurrently with reflex blinks, the procedure potentiated subsequent blinks for >1 hr. Combining HFS with feedback from the… CONTINUE READING