Long-term potentiation and depression of synaptic responses in the rat hippocampus: localization and frequency dependency.

Abstract

1. The consequences of repetitive activation of excitatory synaptic inputs to the CA1 pyramidal cells of rat hippocampus have been studied using in vitro techniques. 2. Single stimulation trains of 100 pulses at rates of 5-100/sec resulted in potentiation of population spike amplitudes lasting the duration of a 5 min test period in thirty-four out of thirty… (More)

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Cite this paper

@article{Dunwiddie1978LongtermPA, title={Long-term potentiation and depression of synaptic responses in the rat hippocampus: localization and frequency dependency.}, author={Thomas V. Dunwiddie and Gordon S Lynch}, journal={The Journal of physiology}, year={1978}, volume={276}, pages={353-67} }