Long-term persistence of human donor alveolar macrophages in lung transplant recipients.

Abstract

BACKGROUND Alveolar macrophages (AMFs) are critical regulators of lung function, and may participate in graft rejection following lung transplantation. Recent studies in experimental animals suggest that most AMFs are self-maintaining cells of embryonic origin, but knowledge about the ontogeny and life span of human AMFs is scarce. METHODS To follow the… (More)
DOI: 10.1136/thoraxjnl-2016-208292

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