Long-term persistence of donor nuclei in a Duchenne muscular dystrophy patient receiving bone marrow transplantation.

@article{Gussoni2002LongtermPO,
  title={Long-term persistence of donor nuclei in a Duchenne muscular dystrophy patient receiving bone marrow transplantation.},
  author={Emanuela Gussoni and Richard R. Bennett and Kristina R Muskiewicz and Todd E. Meyerrose and Jan A Nolta and Irene S Gilgoff and James Stein and Yiu-mo Michael Chan and H G W Lidov and Carsten G B{\"o}nnemann and Arpad von Moers and Glenn E. Morris and Johan T den Dunnen and Jeffrey S. Chamberlain and Louis M. Kunkel and Kenneth Weinberg},
  journal={The Journal of clinical investigation},
  year={2002},
  volume={110 6},
  pages={807-14}
}
Duchenne muscular dystrophy (DMD) is a severe progressive muscle-wasting disorder caused by mutations in the dystrophin gene. Studies have shown that bone marrow cells transplanted into lethally irradiated mdx mice, the mouse model of DMD, can become part of skeletal muscle myofibers. Whether human marrow cells also have this ability is unknown. Here we report the analysis of muscle biopsies from a DMD patient (DMD-BMT1) who received bone marrow transplantation at age 1 year for X-linked severe… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 63 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 57 references

Hematopoietic stem-cell transplantation for the treatment of severe combined immunodeficiency

  • Buckley, R.H
  • N. Engl. J. Med
  • 1999
Highly Influential
8 Excerpts

Bone marrow transplantation corrects osteopetrosis in the carbonic anhydrase II deficiency syndrome

  • C McMahon
  • Blood .
  • 2001
1 Excerpt

Similar Papers

Loading similar papers…