Long term peripheral nerve regeneration using a novel PCL nerve conduit

  title={Long term peripheral nerve regeneration using a novel PCL nerve conduit},
  author={Adam J Reid and Alba C. de Luca and Alessandro Faroni and Sandra Downes and Mingzhu Sun and Giorgio Terenghi and Paul J Kingham},
  journal={Neuroscience Letters},
The gold standard in surgical management of a peripheral nerve gap is currently autologous nerve grafting. This confers patient morbidity and increases surgical time therefore innovative experimental strategies towards engineering a synthetic nerve conduit are welcome. We have developed a novel synthetic conduit made of poly ε-caprolactone (PCL) that has demonstrated promising peripheral nerve regeneration in short-term studies. This material has been engineered to permit translation into… CONTINUE READING
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