Long-term outcome of therapeutic neovascularization using peripheral blood mononuclear cells for limb ischemia.

@article{Moriya2009LongtermOO,
  title={Long-term outcome of therapeutic neovascularization using peripheral blood mononuclear cells for limb ischemia.},
  author={J Moriya and Tohru Minamino and Kaoru Tateno and Naomi Shimizu and Yoichi Kuwabara and Y Sato and Yasushi Saito and Issei Komuro},
  journal={Circulation. Cardiovascular interventions},
  year={2009},
  volume={2 3},
  pages={245-54}
}
BACKGROUND Injection of bone marrow mononuclear cells has been reported to promote neovascularization of ischemic tissues effectively. We found that peripheral blood mononuclear cells were as efficient as bone marrow mononuclear cells for the treatment of limb ischemia in animals and showed that this treatment was feasible and safe in no-option patients with limb ischemia. However, the long-term outcome of such therapy has not been investigated. METHODS AND RESULTS We retrospectively analyzed… CONTINUE READING
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