Long-term outcome of patients with perianal Paget's disease

@article{Marchesa1997LongtermOO,
  title={Long-term outcome of patients with perianal Paget's disease},
  author={Pierenrico Marchesa and Victor Warren Fazio and Soledad Oliart and John R. Goldblum and Ian C. Lavery and Jeffrey W. Milsom},
  journal={Annals of Surgical Oncology},
  year={1997},
  volume={4},
  pages={475-480}
}
Background: Perianal Paget's disease (PPD) is a rare intraepithelial adenocarcinoma with a significant rate of recurrence after treatment and high risk of progression to an invasive cancer. Patients and Methods: Fourteen patients with a mean follow-up longer than 5 years were studied to determine the outcome after surgical treatment. The immunohistochemical accumulation of p53 protein also was assessed in tissue specimens to evaluate its prognostic role in patients with PPD. Results: Four… CONTINUE READING

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