Long-term outcome of patients with monoclonal Ig deposition disease treated with high-dose melphalan and stem cell transplantation

Abstract

Monoclonal Ig deposition disease (MIDD) is a clonal plasma cell dyscrasia in which light-chain and/or heavychain subunits of Igs form non-fibrillar deposits in various tissues, causing organ dysfunction. Kidneys are universally affected, often presenting with proteinuria and rapidly progressing to end-stage renal failure in more than 60% of cases. Extra… (More)
DOI: 10.1038/bmt.2010.82

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