Long-term outcome of biopsy-proven, frequently relapsing minimal-change nephrotic syndrome in children.

@article{Kyrieleis2009LongtermOO,
  title={Long-term outcome of biopsy-proven, frequently relapsing minimal-change nephrotic syndrome in children.},
  author={Henriette A C Kyrieleis and Marije M. L{\"o}wik and Ilse Pronk and Hans R M Cruysberg and Jan Am Kremer and Wim J. G. Oyen and Bert L P van den Heuvel and Jack F. M. Wetzels and Elena Levtchenko},
  journal={Clinical journal of the American Society of Nephrology : CJASN},
  year={2009},
  volume={4 10},
  pages={
          1593-600
        }
}
BACKGROUND AND OBJECTIVES Frequently relapsing and steroid-dependent minimal-change nephrotic syndrome (MCNS) that originates in childhood can persist after puberty in >20% of patients. These patients require immunosuppressive treatment during several decades of their life. We examined long-term adverse effects of persistent nephrotic syndrome and immunosuppressive medications, focusing on renal function, growth, obesity, osteoporosis, hypertension, ocular complications, and fertility in adult… CONTINUE READING

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