Long-term oral exposure to bisphenol A induces glucose intolerance and insulin resistance.

@article{Moon2015LongtermOE,
  title={Long-term oral exposure to bisphenol A induces glucose intolerance and insulin resistance.},
  author={Min Kyong Moon and In-Kyong Jeong and Tae Jung Oh and Hwa young Ahn and Hyun Hee Kim and Young Joo Park and Hak Chul Jang and Kyong Soo Park},
  journal={The Journal of endocrinology},
  year={2015},
  volume={226 1},
  pages={35-42}
}
Bisphenol A (BPA) is a widely used endocrine disruptor. Recent epidemiologic results have suggested an association between exposure to BPA and cardiovascular disease, type 2 diabetes, and obesity. We investigated the in vivo effects of long-term oral exposure to BPA on insulin resistance and glucose intolerance. In the present study, 4- to 6-week-old male mice on a high-fat diet (HFD) were treated with 50 μg/kg body weight per day of BPA orally for 12 weeks. Long-term oral exposure to BPA along… CONTINUE READING
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