Long-term non-invasive ventilation in COPD after acute-on-chronic respiratory failure.

  title={Long-term non-invasive ventilation in COPD after acute-on-chronic respiratory failure.},
  author={G C Funk and Marie-Kathrin Breyer and Otto Chris Burghuber and Eveline Kink and Kathrin Kirchheiner and Robab Kohansal and Ingrid Schmidt and Sylvia Hartl},
  journal={Respiratory medicine},
  volume={105 3},
BACKGROUND COPD patients who remain hypercapnic after acute respiratory failure requiring mechanical ventilation have a poor prognosis. Long-term nocturnal non-invasive ventilation (NIV) may be beneficial for these patients. We hypothesized that stable patients on long-term NIV would experience clinical worsening after withdrawal of NIV. METHODS We included 26 consecutive COPD patients (63 ± 6 years, 58% male, FEV(1) 31 ± 14% predicted) who remained hypercapnic after acute respiratory failure… CONTINUE READING


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