Long-term neuroendocrine and behavioural effects of a single exposure to stress in adult animals.

@article{Armario2008LongtermNA,
  title={Long-term neuroendocrine and behavioural effects of a single exposure to stress in adult animals.},
  author={Antonio Armario and Rosa Mar{\'i}a Escorihuela and Roser Nadal},
  journal={Neuroscience and biobehavioral reviews},
  year={2008},
  volume={32 6},
  pages={1121-35}
}
There is now considerable evidence for long-lasting sequels of stress. A single exposure to high intensity predominantly emotional stressors such as immobilisation in wooden-boards (IMO) induces long-term (days to weeks) desensitization of the hypothalamic-pituitary-adrenal (HPA) response to the same (homotypic) stressor, whereas the response to novel (heterotypic) stressors was enhanced. In addition, long-lasting changes in behaviour have been described after a single exposure to brief or more… CONTINUE READING

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Long-term effects of a single exposure to immobilization stress on the hypothalamic-pituitary-adrenal axis: transcriptional evidence for a progressive desensitization process

  • A. Vallès, O. Martı, A. Armario
  • Eur. J. Neurosci
  • 2003
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