Long term memory profile of disorders associated with dysregulation of the RAS-MAPK signaling cascade.

@article{Alfieri2011LongTM,
  title={Long term memory profile of disorders associated with dysregulation of the RAS-MAPK signaling cascade.},
  author={Paolo Alfieri and Laura Cesarini and Maria Mallardi and Giorgia Piccini and Cristina Caciolo and Chiara Leoni and Nadia Mirante and Francesca Pantaleoni and Maria Christina Digilio and Maria Luigia Gambardella and M Tartaglia and Stefano Vicari and Eugenio Mercuri and Giuseppe Zampino},
  journal={Behavior genetics},
  year={2011},
  volume={41 3},
  pages={423-9}
}
In the present study we evaluated long term memory in twenty individuals with molecularly confirmed diagnosis of Noonan syndrome and LEOPARD syndrome, two disorders caused by mutations in genes coding transducers participating in the RAS-MAPK signaling cascade. The profile of explicit long term memory abilities was investigated using PROMEA, which includes a battery of tests specifically developed to assess memory and learning in verbal, visual and spatial domains. Ten individuals (50%) had… CONTINUE READING

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