Long-term maintenance of weight loss with sibutramine in a GP setting following a specialist guided very-low-calorie diet: a double-blind, placebo-controlled, parallel group study

@article{MathusVliegen2005LongtermMO,
  title={Long-term maintenance of weight loss with sibutramine in a GP setting following a specialist guided very-low-calorie diet: a double-blind, placebo-controlled, parallel group study},
  author={Elisabeht M H Mathus-Vliegen},
  journal={European Journal of Clinical Nutrition},
  year={2005},
  volume={59},
  pages={S31-S39}
}
Objective:Very-low-calorie diets (VLCDs) are used to promote short-term weight loss in obese patients. However, long-term maintenance of weight loss is generally poor. We assessed the efficacy and safety of sibutramine in maintaining weight loss achieved in obese patients by means of a 3-month VLCD.Design:A multicenter double-blind, parallel-group trial conducted over 18 months, following a 3-month open label VLCD run-in.Setting:Eight hospital centers in The Netherlands, with subsequent follow… CONTINUE READING