Long-term magnesium sulfate treatment as protection against hypoxic-ischemic brain injury in seven-day-old rats.

Abstract

OBJECTIVE Our purpose was to study the effects of long-term treatment with magnesium sulfate on hypoxic-ischemic brain damage in newborn rats. STUDY DESIGN Seven-day-old rat pups (n = 120) were exposed to unilateral carotid artery ligation and 2 hours of hypoxia (8% oxygen in 92% nitrogen). Neuronal loss was evaluated in 4 groups. The loading dose group… (More)

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Cite this paper

@article{Sameshima2001LongtermMS, title={Long-term magnesium sulfate treatment as protection against hypoxic-ischemic brain injury in seven-day-old rats.}, author={Hidehisa Sameshima and Tatsuya Ikenoue}, journal={American journal of obstetrics and gynecology}, year={2001}, volume={184 2}, pages={185-90} }