Long-term macrolide therapy in chronic inflammatory airway diseases.

  title={Long-term macrolide therapy in chronic inflammatory airway diseases.},
  author={Phil A Crosbie and M. A. Woodhead},
  journal={The European respiratory journal},
  volume={33 1},
In addition to direct antibacterial actions, 14- and 15-member-ring macrolides have immune modulating effects that appear to be the reason for clinical benefit in diffuse panbronchiolitis. A literature search was conducted for studies of the clinical effectiveness of macrolides in other chronic lung conditions. A number of studies were identified that showed short-term beneficial outcomes or the potential for such outcomes in cystic fibrosis, bronchiectasis, chronic obstructive pulmonary… CONTINUE READING
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