Long-term low-dose angiotensin converting enzyme inhibitor treatment increases vascular cyclic guanosine 3',5'-monophosphate.

Abstract

We investigated functional changes in aortic preparations of spontaneously hypertensive rats treated in utero and subsequently up to 20 weeks of age with the angiotensin converting enzyme (ACE) inhibitors ramipril (0.01 and 1 mg/kg per day) and perindopril (0.01 mg/kg per day). Early-onset treatment with the high dose of ramipril inhibited aortic ACE… (More)

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@article{Gohlke1993LongtermLA, title={Long-term low-dose angiotensin converting enzyme inhibitor treatment increases vascular cyclic guanosine 3',5'-monophosphate.}, author={Petra Gohlke and V Lamberty and Ingo Kuwer and Sebastian Bartenbach and Amanda Schnell and Will Linz and Bernward A. Sch{\"o}lkens and Gemma Maria Wiemer and Tina Unger}, journal={Hypertension}, year={1993}, volume={22 5}, pages={682-7} }