Long-term intravesical adjuvant chemotherapy further reduces recurrence rate compared with short-term intravesical chemotherapy and short-term therapy with Bacillus Calmette-Guérin (BCG) in patients with non-muscle-invasive bladder carcinoma.

@article{Friedrich2007LongtermIA,
  title={Long-term intravesical adjuvant chemotherapy further reduces recurrence rate compared with short-term intravesical chemotherapy and short-term therapy with Bacillus Calmette-Gu{\'e}rin (BCG) in patients with non-muscle-invasive bladder carcinoma.},
  author={Martin Gunter Friedrich and Uwe Pichlmeier and Hartwig E. Schwaibold and Stefan Conrad and Hartwig Huland},
  journal={European urology},
  year={2007},
  volume={52 4},
  pages={
          1123-29
        }
}
OBJECTIVE We present a randomised, parallel group, multicentre phase 4 trial comparing short- and long-term chemoprophylaxis with Mitomycin C (MMC) with short-term immunoprophylaxis with Bacillus Calmette-Guérin (BCG) after transurethral resection of the bladder for non-muscle-invasive bladder carcinoma. METHODS Four hundred ninety-five patients with intermediate- to high-risk non-muscle-invasive bladder cancer (recurrent and/or multifocal pTaG1, TaG2-3, and T1G1-3) were randomised to BCG… CONTINUE READING
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