Long-term inhibition of glioma growth by systemic administration of human PEX.

@article{Pluderi2003LongtermIO,
  title={Long-term inhibition of glioma growth by systemic administration of human PEX.},
  author={Mauro Pluderi and Valeria Lucini and Dario Caronzolo and Marilou Pannacci and Francesco Vittorio Costa and Giorgio Carrabba and Carlo Giussani and Silvia Grosso and Federica Colleoni and Francesco Scaglione and Roberto Matteo Villani and Andreas Bikfalvi and Lorenzo Bello},
  journal={Journal of neurosurgical sciences},
  year={2003},
  volume={47 2},
  pages={69-78}
}
AIM The growth of gliomas depends on the balance of factors stimulating or inhibiting angiogenesis, tumor cell invasion and proliferation. The administration of endogenous inhibitors to experimental human gliomas in animal models resulted in a significant inhibition of tumor growth. It is becoming apparent that resistance can develop over time to many types of endogenous inhibitors and seems to be influenced by the tumor type and system of delivery. METHODS We recently isolated a potent… CONTINUE READING