Long-term inhalation toxicity of hydrazine.

  title={Long-term inhalation toxicity of hydrazine.},
  author={E H Vernot and James D. MacEwen and Richard H. Bruner and C C Haun and E R Kinkead and D. E. Prentice and Acheson Hall and Ronald E Schmidt and Robert L Eason and Gene B. Hubbard},
  journal={Fundamental and applied toxicology : official journal of the Society of Toxicology},
  volume={5 6 Pt 1},
Year-long intermittent exposures of rats, mice, hamsters, and dogs to hydrazine were conducted using concentrations of 0.05, 0.25, 1.0, and 5.0 ppm. Rats were held 18 months postexposure; hamsters, 1 year postexposure; mice, 15 months postexposure; and dogs, 38 months postexposure. Male and female rats exhibited dose-dependent incidences of benign nasal adenomatous polyps and smaller numbers of malignant nasal epithelial tumors after 1 year of exposure to hydrazine and 18 months postexposure… CONTINUE READING


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