Long-term ingestion of ammonium increases acetylglutamate and urea levels without affecting the amount of carbamoyl-phosphate synthase.

@article{Felipo1988LongtermIO,
  title={Long-term ingestion of ammonium increases acetylglutamate and urea levels without affecting the amount of carbamoyl-phosphate synthase.},
  author={Vicente Felipo and Mª Dolores Mi{\~n}ana and Santiago Grisol{\^i}a},
  journal={European journal of biochemistry},
  year={1988},
  volume={176 3},
  pages={567-71}
}
Rats were fed the following diets: standard (20% protein), high-protein (80%), protein-free, standard plus ammonium and protein-free plus ammonium for six weeks. The standard plus ammonium diet was prepared to contain ammonia equivalent to that supplied by the high-protein diet. Addition of ammonium acetate (20% by mass) to the 20% protein or protein-free diets results in 2.3- and 10-fold increases of urea excretion respectively, without increase of carbamoyl-phosphate synthase. Supplementation… CONTINUE READING
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