Long-term improvement of arterial wall characteristics in patients with diabetes mellitus type 1 using cyclic, intermittent treatment with a low-dose fluvastatin and valsartan combination.

@article{Savic2015LongtermIO,
  title={Long-term improvement of arterial wall characteristics in patients with diabetes mellitus type 1 using cyclic, intermittent treatment with a low-dose fluvastatin and valsartan combination.},
  author={Veljko J. Savic and Miodrag Jani{\'c} and Mojca Lunder and Karin Kanc and Andrej Jane{\vz} and Barbara Er{\vz}en and Falko H. Herrmann},
  journal={Experimental and therapeutic medicine},
  year={2015},
  volume={10 3},
  pages={
          1207-1211
        }
}
Improvement of arterial wall (AW) characteristics decreases cardiovascular risk. In a previous study, it was observed that AW characteristics in patients with diabetes mellitus type 1 are significantly improved by short-term treatment with a low-dose combination of fluvastatin and valsartan. Additionally, a unique phenomenon of prolonged effect after treatment discontinuation was suggested. The present study tested whether repeated treatm ent after a certain period results in the same… CONTINUE READING

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