Long-term impact of pneumococcal polysaccharide vaccination on nasopharyngeal carriage in children previously vaccinated with various pneumococcal conjugate vaccine regimes.

@article{Boelsen2015LongtermIO,
  title={Long-term impact of pneumococcal polysaccharide vaccination on nasopharyngeal carriage in children previously vaccinated with various pneumococcal conjugate vaccine regimes.},
  author={Laura K. Boelsen and Eileen M Dunne and Karen Elaine Lamb and Kathryn J Bright and Yin Bun Cheung and Lisi V Tikoduadua and Fiona M Russell and Edward Kim Mulholland and Paul Licciardi and Catherine Satzke},
  journal={Vaccine},
  year={2015},
  volume={33 42},
  pages={5708-5714}
}
Previously, the Fiji Pneumococcal Project (FiPP) evaluated reduced dose immunization schedules that incorporated pneumococcal protein conjugate and/or polysaccharide vaccine (PCV7 and 23vPPV, respectively). Immune hyporesponsiveness was observed in children vaccinated with 23vPPV at 12 months of age compared with children who did not receive 23vPPV. Here we assess the long-term impact of 23vPPV vaccination on nasopharyngeal carriage rates and densities of Streptococcus pneumoniae, Haemophilus… CONTINUE READING
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