Long-term impact of CMV infection on allografts and on patient survival in renal transplant patients with protocol biopsies.

@article{Erdbrgger2015LongtermIO,
  title={Long-term impact of CMV infection on allografts and on patient survival in renal transplant patients with protocol biopsies.},
  author={Uta Erdbr{\"u}gger and Irina Scheffner and Michael 4 Mengel and Anke Schwarz and Hermann Haller and Wilfried Gwinner},
  journal={American journal of physiology. Renal physiology},
  year={2015},
  volume={309 11},
  pages={F925-32}
}
Cytomegalovirus (CMV) infection is a frequent complication of early posttransplantation. This study examines its impact on chronic allograft changes, long-term graft loss, and patient survival. We studied 594 patients who had protocol biopsies at 6 wk, and 3 and 6 mo posttransplantation. Chronic allograft changes were evaluated according to the updated Banff classification [interstitial fibrosis/tubular atrophy (IF/TA), vascular and glomerular lesions]. Follow-up data were available for up to… CONTINUE READING
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