Long-term hematologic reconstitution after autologous peripheral blood progenitor cell transplantation: a comparison between controlled-rate freezing and uncontrolled-rate freezing at 80 degrees C.

@article{Montanari2003LongtermHR,
  title={Long-term hematologic reconstitution after autologous peripheral blood progenitor cell transplantation: a comparison between controlled-rate freezing and uncontrolled-rate freezing at 80 degrees C.},
  author={Mauro Montanari and Debora Capelli and Antonella Poloni and Danilo Massidda and Marino Brunori and Luca Spitaleri and Massimo Offidani and Moira Lucesole and Maria Cristiana Masia and Florinda Balducci and Cristina Refe and Mario Piani and Pietro Leoni and Attilio Olivieri},
  journal={Transfusion},
  year={2003},
  volume={43 1},
  pages={42-9}
}
BACKGROUND The most widely used system for peripheral blood progenitor cell (PBPC) cryopreservation is controlled-rate freezing (CRF). Uncontrolled-rate freezing (URF) at -80 degrees C has also been used, but its clinical impact has not been studied sufficiently yet. STUDY DESIGN AND METHODS Two groups of patients were compared: Group A consisted of 69 patients autotransplanted with PBPCs cryopreserved with CRF; Group B consisted of 192 patients autotransplanted with PBPCs cryopreserved with… CONTINUE READING

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