Long-term follow-up of sustained responders to interferon therapy, in patients with chronic hepatitis C.

@article{Toyoda2000LongtermFO,
  title={Long-term follow-up of sustained responders to interferon therapy, in patients with chronic hepatitis C.},
  author={Hidenori Toyoda and Takashi Kumada and Alejandro Tokuda and Yuji Horiguchi and Hitoshi Nakano and Takashi Honda and S. Hidaka Z. Hu H. Kato K. Nakano and Kazuhiko Hayashi and Yosiaki Katano and Isao Nakano and Takahiro Hayakawa and Daisaku Nishimura and Karen Kato and Kazumi Imada and Masami Imoto and Yoshihide Fukuda},
  journal={Journal of viral hepatitis},
  year={2000},
  volume={7 6},
  pages={414-9}
}
Interferon (IFN) therapy has been proven to induce the normalization of serum alanine aminotransferase (ALT) levels and to eradicate the hepatitis C virus (HCV) in some patients with chronic hepatitis C, and these patients are usually defined as 'sustained responders'. However, there have been some reports of hepatocellular carcinoma (HCC) in these patients, and the development of HCC remains life-threatening in patients who clear HCV. We analysed the long-term prognoses of patients with… CONTINUE READING

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