Long-term follow-up of front-line treatment of hairy cell leukemia with 2-chlorodeoxyadenosine.

@article{Zinzani2004LongtermFO,
  title={Long-term follow-up of front-line treatment of hairy cell leukemia with 2-chlorodeoxyadenosine.},
  author={Pier Luigi Zinzani and M Kendouci Tani and Enrica Marchi and Vittorio Stefoni and Lapo Alinari and Gerardo Musuraca and Annalisa Gabriele and Stefano A Pileri and Michele Baccarani},
  journal={Haematologica},
  year={2004},
  volume={89 3},
  pages={309-13}
}
BACKGROUND AND OBJECTIVES Although remission of hairy cell leukemia (HCL) after treatment with 2-chlorodeoxyadenosine (2-CdA) appears to be long lasting, few reports currently provide results from follow-up exceeding 5 years. DESIGN AND METHODS We reviewed our HCL patients treated with front-line 2-CdA (by 2-hour infusion) either for 5 consecutive days at 0.14 mg/kg/day (daily subset, n=21) or once a week at 0.14 mg/kg for 5 cycles (weekly subset, n=16). RESULTS Of the 37 eligible patients… CONTINUE READING

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