Long-term follow-up of bone mineral density in Addison's disease.

@article{Jdar2003LongtermFO,
  title={Long-term follow-up of bone mineral density in Addison's disease.},
  author={Esteban J{\'o}dar and Mar{\'i}a Pilar Ruiz Valdepe{\~n}as and Guillermo Oller Martinez and Antonino Jara and Federico Hawkins},
  journal={Clinical endocrinology},
  year={2003},
  volume={58 5},
  pages={617-20}
}
BACKGROUND AND AIMS There is conflicting evidence regarding the long-term effects of long-term glucocorticoid replacement therapy (GRT) on bone mineral density (BMD) in patients with chronic adrenal insufficiency. Our aim was to evaluate bone turnover and changes in BMD in patients on GRT. PATIENTS AND METHODS We have studied 25 subjects (six men, 19 women; aged 62.4 +/- 11.3 years, duration of disease 21.7 +/- 11.7 years, fasting cortisol 63 +/- 36 nmol/l) on GRT (hydrocortisone 30 mg/day or… CONTINUE READING

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