Long-term follow-up of IgM monoclonal gammopathy of undetermined significance.

  title={Long-term follow-up of IgM monoclonal gammopathy of undetermined significance.},
  author={Robert A Kyle and Terry M. Therneau and S Vincent Rajkumar and Janice R Offord and Dirk Russell Larson and Matthew F. Plevak and Lee Joseph Melton},
  journal={Seminars in oncology},
  volume={30 2},
The current study was conducted to determine the risk of adverse outcomes among patients with monoclonal gammopathy of undetermined significance (MGUS) of the IgM class. Two hundred thirteen patients with IgM MGUS were identified in southeastern Minnesota from 1960 to 1994. The primary end point was progression to lymphoma or a related disorder assessed by the Kaplan-Meier method. Patients were followed for a total of 1,567 person-years (median, 6.3 years per subject). Seventeen patients… CONTINUE READING
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