Long-term follow-up of Ewing's sarcoma of bone treated with combined modality therapy.

@article{Kinsella1991LongtermFO,
  title={Long-term follow-up of Ewing's sarcoma of bone treated with combined modality therapy.},
  author={Timothy J. Kinsella and James S. Miser and Bridget Waller and David J Venzon and Eli J. Glatstein and L Weaver-McClure and Marc E. Horowitz},
  journal={International journal of radiation oncology, biology, physics},
  year={1991},
  volume={20 3},
  pages={389-95}
}
Between 1968 and 1980, 107 consecutive patients with Ewing's sarcoma of bone were entered on three sequential combined modality treatment protocols (S2, S3, S4) at the National Cancer Institute (NCI). Protocol treatment involved 4 cycles of two drug [cyclophosphamide (CTX) and vincristine (VCR)] or three drug [CTX and VCR with either actinomycin-D (ACT-D) or doxorubicin (ADR)] regimens and local irradiation (50 Gy) to the involved bone. Eighty patients presented with localized disease and 27… CONTINUE READING

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