Long-term follow-up (42 months) of chronic anal fissure after healing with botulinum toxin.

@article{Mnguez2002LongtermF,
  title={Long-term follow-up (42 months) of chronic anal fissure after healing with botulinum toxin.},
  author={Miguel M{\'i}nguez and Belen Herreros and Alejandro Esp{\'i} and Eduardo Garc{\'i}a-Granero and Vicente S{\'a}nchiz and Francisco E Mora and Salvador Lled{\'o} and Adolfo Benages},
  journal={Gastroenterology},
  year={2002},
  volume={123 1},
  pages={112-7}
}
BACKGROUND & AIMS Botulinum toxin is an effective treatment in idiopathic chronic anal fissure, but the long-term outcome after healing is not well documented. We analyzed the long-term outcome of patients in whom an anal fissure had healed after botulinum toxin injection and the factors contributing to recurrence. METHODS Fifty-seven patients who had completely healed 6 months after injection of botulinum toxin were reassessed every 6 months. The follow-up was 42 months in all patients… CONTINUE READING