Long-term facilitation in obstructive sleep apnea patients during NREM sleep.

  title={Long-term facilitation in obstructive sleep apnea patients during NREM sleep.},
  author={Salah E Aboubakr and Addison Taylor and Rosie Ford and S Siddiqi and Mohamed S Badr},
  journal={Journal of applied physiology},
  volume={91 6},
Repetitive hypoxia followed by persistently increased ventilatory motor output is referred to as long-term facilitation (LTF). LTF is activated during sleep after repetitive hypoxia in snorers. We hypothesized that LTF is activated in obstructive sleep apnea (OSA) patients. Eleven subjects with OSA (apnea/hypopnea index = 43.6 +/- 18.7/h) were included. Every subject had a baseline polysomnographic study on the appropriate continuous positive airway pressure (CPAP). CPAP was retitrated to… CONTINUE READING


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